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Advances and Future Directions in Understanding Associations Between Stressful Events and Cortical Thickness in Psychosis Risk

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      Linked Article

      • Life Event Stress and Reduced Cortical Thickness in Youth at Clinical High Risk for Psychosis and Healthy Control Subjects
        Biological Psychiatry: Cognitive Neuroscience and NeuroimagingVol. 7Issue 2
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          A decline in cortical thickness during early life appears to be a normal neuromaturational process. Accelerated cortical thinning has been linked with conversion to psychosis among individuals at clinical high risk for psychosis (CHR-P). Previous research indicates that exposure to life event stress (LES) is associated with exaggerated cortical thinning in both healthy and clinical populations, and LES is also linked with conversion to psychosis in CHR-P. To date, there are no reports on the relationship of LES with cortical thickness in CHR-P.
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