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Article info
Publication history
Accepted:
December 8,
2021
Received:
December 3,
2021
Identification
Copyright
© 2021 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.
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- Association Between Genetic Risk for Type 2 Diabetes and Structural Brain Connectivity in Major Depressive DisorderBiological Psychiatry: Cognitive Neuroscience and NeuroimagingVol. 7Issue 3
- PreviewMajor depressive disorder (MDD) and type 2 diabetes mellitus (T2D) are known to share clinical comorbidity and to have genetic overlap. Besides their shared genetics, both diseases seem to be associated with alterations in brain structural connectivity and impaired cognitive performance, but little is known about the mechanisms by which genetic risk of T2D might affect brain structure and function and if they do, how these effects could contribute to the disease course of MDD.
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