Abstract
Keywords
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Biological Psychiatry: Cognitive Neuroscience and NeuroimagingReferences
- Cross-sex testosterone therapy in ovariectomized mice: addition of low-dose estrogen preserves bone architecture.American Journal of Physiology-Endocrinology and Metabolism. 2017; 313: E540-E551
- Addition of Estradiol to Cross-Sex Testosterone Therapy Reduces Atherosclerosis Plaque Formation in Female ApoE−/− Mice.Endocrinology. 2018; 159: 754-762
- Standards of Care for the Health of Transsexual, Transgender, and Gender-Nonconforming People, Version 7.International Journal of Transgenderism. 2012; 13: 165-232
- Association of Gender-Affirming Hormone Therapy With Depression, Thoughts of Suicide, and Attempted Suicide Among Transgender and Nonbinary Youth.Journal of Adolescent Health. 2022; 70: 643-649
- A Systematic Review of the Effects of Hormone Therapy on Psychological Functioning and Quality of Life in Transgender Individuals.Transgender Health. 2016; 1: 21-31
- Effect of cross-sex hormones on the quality of life, depression and anxiety of transgender individuals: a quantitative systematic review.JBI Database of Systematic Reviews and Implementation Reports. 2019; 17: 1826-1854
Serano J (2007): Whipping Girl, 2nd ed. Berekeley, CA: Seal Press.
- Hormonal Treatment Reduces Psychobiological Distress in Gender Identity Disorder, Independently of the Attachment Style.The Journal of Sexual Medicine. 2013; 10: 3049-3058
- Transgender rights rely on inclusive language.Science. 2021; 374: 1568-1569
State of Florida Agency for Health Care Administration (2022): Agency for Health Care Administration Releases Generally Accepted Professional Medical Standards Determination on the Treatment of Gender Dysphoria. pp 1–2.
- The Misuse of Gender Dysphoria: Toward Greater Conceptual Clarity in Transgender Health.Perspect Psychol Sci. 2021; 16: 1159-1164
- On the Basis of Gender: A Medical-Legal Review of Barriers to Healthcare for Transgender and Gender-Expansive Patients.Social Work in Public Health. 2021; 36: 615-627
- Diverse Roles for Sex Hormone-Binding Globulin in Reproduction.Biology of Reproduction. 2011; 85: 431-441
- Methods for long-term 17β-estradiol administration to mice.General and Comparative Endocrinology. 2012; 175: 188-193
- Progesterone Is Important for Transgender Women’s Therapy—Applying Evidence for the Benefits of Progesterone in Ciswomen.The Journal of Clinical Endocrinology & Metabolism. 2019; 104: 1181-1186
Deutsch M (2016): Guidelines for the Primary and Gender-Affirming Care of Transgender and Gender Nonbinary People, 2nd ed. UCSF Transgender Care, Department of Family and Community Medicine, University of California San Francisco. Retrieved from https://transcare.ucsf.edu/sites/transcare.ucsf.edu/files/Transgender-PGACG-6-17-16.pdf
- Associations between transition-specific stress experience, nocturnal decline in ambulatory blood pressure, and C-reactive protein levels among transgender men.Am J Hum Biol. 2012; 24: 52-61
- Stigma and diurnal cortisol among transitioning transgender men.Psychoneuroendocrinology. 2017; 82: 59-66
- Experiences of Transgender-Related Discrimination and Implications for Health: Results From the Virginia Transgender Health Initiative Study.Am J Public Health. 2013; 103: 1820-1829
- Attempted Suicide Among Transgender Persons: The Influence of Gender-Based Discrimination and Victimization.Journal of Homosexuality. 2006; 51: 53-69
- Expecting Rejection: Understanding the Minority Stress Experiences of Transgender and Gender-Nonconforming Individuals.Transgender Health. 2016; 1: 151-164
- The relationship between family acceptance-rejection and transgender youth psychosocial functioning.Clinical Practice in Pediatric Psychology. 2019; 7: 267-277
- The buffer of resilience in the relations of gender-related discrimination, rejection, and victimization with depression among Chinese transgender and gender non-conforming individuals.Journal of Affective Disorders. 2021; 283: 335-343
- Healthcare mistreatment and avoidance in trans masculine adults: The mediating role of rejection sensitivity.Psychology of Sexual Orientation and Gender Diversity. 2018; 5: 471-481
- Does Rejection Hurt? An fMRI Study of Social Exclusion.Science. 2003; 302: 290-292
Williams KD (2009): Chapter 6 Ostracism. Advances in Experimental Social Psychology, vol. 41. Elsevier, pp 275–314.
- Ostracism: Consequences and Coping.Curr Dir Psychol Sci. 2011; 20: 71-75
- The Social Risk Hypothesis of Depressed Mood: Evolutionary, Psychosocial, and Neurobiological Perspectives.Psychological Bulletin. 2003; 129: 887-913
- The consequences of perceived discrimination for psychological well-being: A meta-analytic review.Psychological Bulletin. 2014; 140: 921-948
- More than skin deep”: stress neurobiology and mental health consequences of racial discrimination.Stress. 2015; 18: 1-10
- Structural racism and health inequities in the USA: evidence and interventions.The Lancet. 2017; 389: 1453-1463
- Toward an Interactional Description of Depression.null. 1976; 39: 28-40
Brooks VR (1981): Minority Stress and Lesbian Women. Lexington, Mass.: Lexington Books.
- Prejudice, social stress, and mental health in lesbian, gay, and bisexual populations: Conceptual issues and research evidence.Psychological Bulletin. 2003; 129: 674-697
- A conceptual framework for clinical work with transgender and gender nonconforming clients: An adaptation of the Minority Stress Model.Professional Psychology: Research and Practice. 2012; 43: 460-467
- The buffering role of social support on the associations among discrimination, mental health, and suicidality in a transgender sample.International Journal of Transgenderism. 2017; 18: 39-52
- Mental health and resilience in transgender individuals: What type of support makes a difference?.Journal of Family Psychology. 2019; 33: 954-964
- Neural mechanisms of social homeostasis.Ann NY Acad Sci. 2019; 1457: 5-25
- Social stress models in rodents: Towards enhanced validity.Neurobiology of Stress. 2017; 6: 104-112
- Brain Estradiol Content in Newborn Rats: Sex Differences, Regional Heterogeneity, and Possible de Novo Synthesis by the Female Telencephalon.Endocrinology. 2004; 145: 2906-2917
- Influences of non-canonical neurosteroid signaling on developing neural circuits.Current Opinion in Neurobiology. 2016; 40: 103-110
- Function of nuclear sex hormone receptors in gene regulation.Cancer Chemother Pharmacol. 2005; 56: 4-9
- Oestrogen engages brain MC4R signalling to drive physical activity in female mice.Nature. 2021; 599: 131-135
- Gene regulation by gonadal hormone receptors underlies brain sex differences.Nature. 2022; 606: 153-159
- Molecular, spatial, and functional single-cell profiling of the hypothalamic preoptic region.Science. 2018; 362eaau5324
- Hormones, genes, and behavior.Proceedings of the National Academy of Sciences. 1997; 94: 14213-14216
- The G-protein-coupled estrogen receptor GPER in health and disease.Nat Rev Endocrinol. 2011; 7: 715-726
- Estrogen-dependent up-regulation of TRPA1 and TRPV1 receptor proteins in the rat endometrium.J Mol Endocrinol. 2016; 56: 135-149
- Membrane-initiated estrogen signaling via Gq-coupled GPCR in the central nervous system.Steroids. 2019; 142: 77-83
- Social behavior in context: Hormonal modulation of behavioral plasticity and social competence.Integrative and Comparative Biology. 2009; 49: 423-440
- Neural mechanisms of persistent aggression.Current Opinion in Neurobiology. 2022; 73102526
- Periodic Remodeling in a Neural Circuit Governs Timing of Female Sexual Behavior.Cell. 2019; 179 (e16): 1393-1408
- Hormonal gain control of a medial preoptic area social reward circuit.Nat Neurosci. 2017; 20: 449-458
- Molecular basis of agonism and antagonism in the oestrogen receptor.Nature. 1997; 389: 753-758
- Liganded and unliganded activation of estrogen receptor and hormone replacement therapies.Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2011; 1812: 1054-1060
- Estrogen Administered Neonatally Affects Adult Sexual Behavior in Male and Female Rats.Science. 1964; 144: 185-187
- Activation of Feminine Sexual Behavior in Castrated Male Rats by Intrahypothalamic Implants of Estradiol Benzoate.Neuroendocrinology. 1979; 28: 228-233
- Medial preoptic area in mice is capable of mediating sexually dimorphic behaviors regardless of gender.Nat Commun. 2018; 9: 279
- Functional circuit architecture underlying parental behaviour.Nature. 2018; 556: 326-331
- A Starring Role for Microglia in Brain Sex Differences.Neuroscientist. 2015; 21: 306-321
- Depression, Estrogens, and Neuroinflammation: A Preclinical Review of Ketamine Treatment for Mood Disorders in Women.Front Psychiatry. 2022; 12797577
- Estrogen receptor-α mediates the brain antiinflammatory activity of estradiol.Proc Natl Acad Sci USA. 2003; 100: 9614-9619
Bruce-Keller AJ, Keeling JL, Keller JN, Huang FF, Camondola S, Mattson MP (2000): Antiinflammatory Effects of Estrogen on Microglial Activation. 141: 11.
- Aromatase in the Brain: Not Just for Reproduction Anymore.Journal of Neuroendocrinology. 2008; 20: 705-712
- Neuroprotection mediated through estrogen receptor-α in astrocytes.Proc Natl Acad Sci USA. 2011; 108: 8867-8872
- Estrogen receptor alpha, G‐protein coupled estrogen receptor 1, and aromatase: Developmental, sex, and region‐specific differences across the rat caudate–putamen, nucleus accumbens core and shell.J Comp Neurol. 2021; 529: 786-801
- Immunolocalization of Estrogen Receptor β in the Mouse Brain: Comparison with Estrogen Receptor α.Endocrinology. 2003; 144: 2055-2067
- Androgen-Dependent Excitability of Mouse Ventral Hippocampal Afferents to Nucleus Accumbens Underlies Sex-Specific Susceptibility to Stress.Biological Psychiatry. 2020; 87: 492-501
- Sex Differences and Opposite Effects of Stress on Dendritic Spine Density in the Male Versus Female Hippocampus.J Neurosci. 2001; 21: 6292-6297
- The influence of stress and gonadal hormones on neuronal structure and function.Hormones and Behavior. 2015; 76: 118-124
- Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: An in situ hybridization study.J Comp Neurol. 1990; 294: 76-95
- Alteration in the Hypothalamic-Pituitary-Ovarian Axis in Depressed Women.Arch Gen Psychiatry. 2000; 57: 1157
- Sex differences in anxiety and depression: Role of testosterone.Frontiers in Neuroendocrinology. 2014; 35: 42-57
- Testosterone replacement therapy for hypogonadal men with SSRI-refractory depression.Journal of Affective Disorders. 1998; 48: 157-161
- Clinician vs Self-ratings of Hirsutism in Patients With Polycystic Ovarian Syndrome: Associations With Quality of Life and Depression.JAMA Dermatol. 2016; 152: 783
- The prevalence of eating disorders in women with facial hirsutism: An epidemiological cohort study.Int J Eat Disord. 2008; 41: 427-431
- Venlafaxine vs. fluoxetine in postmenopausal women with major depressive disorder: an 8-week, randomized, single-blind, active-controlled study.BMC Psychiatry. 2021; 21: 260
- Menopausal depression: comparison of hormone replacement therapy and hormone replacement therapy plus fluoxetine.Chinese Medical Journal. 2004; 117: 189-194
- Increase in Prefrontal Cortex Serotonin 2A Receptors Following Estrogen Treatment in Postmenopausal Women.AJP. 2003; 160: 1522-1524
- Relative Antidepressant Efficacy of Venlafaxine and SSRIs: Sex-Age Interactions.Journal of Women’s Health. 2005; 14: 609-616
- Affective changes with estrogen and androgen replacement theraphy in surgically menopausal women.Journal of Affective Disorders. 1988; 14: 177-187
- Effects of Hormone Therapy on Cognition and Mood in Recently Postmenopausal Women: Findings from the Randomized, Controlled KEEPS–Cognitive and Affective Study.PLoS Med. 2015; 12e1001833
- Animal models of major depression and their clinical implications.Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2016; 64: 293-310
- Decreased plasma BDNF level in depressive patients.Journal of Affective Disorders. 2007; 101: 239-244
- Neuronal and behavioral plasticity: the role of serotonin and BDNF systems tandem.Expert Opinion on Therapeutic Targets. 2019; 23: 227-239
- Receptor Mechanisms Mediating Non-Genomic Actions of Sex Steroids.Semin Reprod Med. 2007; 25: 139-153
- Differential effects of fluoxetine and venlafaxine on memory recognition: Possible mechanisms of action.Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2012; 38: 159-167
- Deficiency in Androgen Receptor Aggravates the Depressive-Like Behaviors in Chronic Mild Stress Model of Depression.Cells. 2019; 8: 1021
- Androgen deficit changes the response to antidepressant drugs in tail suspension test in mice.The Aging Male. 2020; 23: 1259-1265
- Distribution of androgen receptor mRNA in the prepubertal male and female mouse brain.J Neuroendocrinology. 2021; 33https://doi.org/10.1111/jne.13063
- Gene Expression of Progesterone Receptor Isoforms in the Rat Brain.Hormones and Behavior. 1994; 28: 454-463
- Comparative distribution of estrogen receptor-α and -β mRNA in the rat central nervous system.J Comp Neurol. 1997; 388: 507-525
Tinbergen N (1951): The Study of Instinct. Clarendon Press/Oxford University Press.
Roughgarden J (2004): Evolution’s Rainbow: Diversity, Gender, and Sexuality in Nature and People. University of California Press.
- Pheromonal communication in vertebrates.Nature. 2006; 444: 308-315
- The contribution of ultrasonic vocalizations to mouse courtship.Current Opinion in Neurobiology. 2016; 38: 1-5
- The Faculty of Language: What Is It, Who Has It, and How Did It Evolve?.Science. 2002; 298: 1569-1579
- SLEAP: A deep learning system for multi-animal pose tracking.Nat Methods. 2022; 19: 486-495
Willmore L, Cameron C, Yang J, Witten I, Falkner A (2022): Behavioral and dopaminergic signatures of resilience. bioRxiv. https://doi.org/10.1101/2022.03.18.484885
- High-density multi-fiber photometry for studying large-scale brain circuit dynamics.Nat Methods. 2019; 16: 553-560
- Leveraging calcium imaging to illuminate circuit dysfunction in addiction.Alcohol. 2019; 74: 47-63
- Next-generation GRAB sensors for monitoring dopaminergic activity in vivo.Nat Methods. 2020; 17: 1156-1166
- The Steroid/Peptide Theory of Social Bonds: Integrating testosterone and peptide responses for classifying social behavioral contexts.Psychoneuroendocrinology. 2011; 36: 1265-1275
- The “Challenge Hypothesis”: Theoretical Implications for Patterns of Testosterone Secretion, Mating Systems, and Breeding Strategies.The American Naturalist. 1990; 136: 829-846
- Average Associations Between Sexual Desire, Testosterone, and Stress in Women and Men Over Time.Arch Sex Behav. 2018; 47: 1613-1631
- Beyond sex and aggression: testosterone rapidly matches behavioural responses to social context and tries to predict the future.Proc R Soc B. 2022; 28920220453
- `They Don’t Like Our Kind’: Consequences of Being Ostracized While Possessing a Group Membership.Group Processes & Intergroup Relations. 2009; 12: 111-127
- A Meta-Analytic Review of Social Identification and Health in Organizational Contexts.Pers Soc Psychol Rev. 2017; 21: 303-335
- Neural control of affiliative touch in prosocial interaction.Nature. 2021; 599: 262-267
- Gonads and strife: Sex hormones vary according to sexual orientation for women and stress indices for both sexes.Psychoneuroendocrinology. 2016; 72: 119-130
- Estrogens, Aging, and Working Memory.Curr Psychiatry Rep. 2018; 20: 109
- Effects of sex steroid hormones on memory.Acta Neurobiologiae Experimentalis. 2020; 80: 117-128
- Mechanisms underlying the rapid effects of estradiol and progesterone on hippocampal memory consolidation in female rodents.Hormones and Behavior. 2018; 104: 100-110
Hamson DK, Roes MM, Galea LAM (2016): Sex Hormones and Cognition: Neuroendocrine Influences on Memory and Learning. In: Terjung R, editor. Comprehensive Physiology, 1st ed. Wiley, pp 1295–1337.
- Why estrogens matter for behavior and brain health.Neuroscience & Biobehavioral Reviews. 2017; 76: 363-379
- Sex differences in episodic memory in early midlife: impact of reproductive aging.Menopause. 2017; 24: 400-408
- Menstrual cycle influence on cognitive function and emotion processing—from a reproductive perspective.Front Neurosci. 2014; 8https://doi.org/10.3389/fnins.2014.00380
- Progesterone rapidly alters the use of place and response memory during spatial navigation in female rats.Hormones and Behavior. 2022; 140105137
- Progesterone and human cognition.Climacteric. 2018; 21: 333-340
- The role of progesterone in memory: An overview of three decades.Neuroscience & Biobehavioral Reviews. 2015; 49: 193-204
Hua JT, Hildreth KL, Pelak VS (2016): Effects of Testosterone Therapy on Cognitive Function in Aging: A Systematic Review. Cognitive and Behavioral Neurology 29: 122–138.
- Subjective cognitive decline higher among sexual and gender minorities in the United States, 2015–2018.A&D Transl Res & Clin Interv. 2021; 7https://doi.org/10.1002/trc2.12197
- Correlates of Subjective Cognitive Decline in Lesbian, Gay, Bisexual, and Transgender Older Adults.Journal of Alzheimer’s Disease. 2018; 64: 91-102
- The Link between Estradiol and Neuroplasticity in Transgender Women after Gender-Affirming Surgery: A Bimodal Hypothesis.Neuroendocrinology. 2020; 110: 489-500
- Androgen (dihydrotestosterone)–mediated regulation of food intake and obesity in female mice.The Journal of Steroid Biochemistry and Molecular Biology. 2013; 138: 100-106
- Diverse actions of estradiol on anorexigenic and orexigenic hypothalamic arcuate neurons.Hormones and Behavior. 2018; 104: 146-155
- Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction.Cell Metabolism. 2011; 14: 453-465
- Estradiol Regulates Brown Adipose Tissue Thermogenesis via Hypothalamic AMPK.Cell Metabolism. 2014; 20: 41-53
González-García I, Contreras C, Estévez-Salguero Á, Ruíz-Pino F, Colsh B, Pensado I, et al. (2018): Estradiol Regulates Energy Balance by Ameliorating Hypothalamic Ceramide-Induced ER Stress. Cell Reports 25: 413-423.e5.
- Patients’ and professionals’ experiences and perspectives of obesity in health-care settings: a synthesis of current research: Patients’and professionals’ experiences.Health Expectations. 2013; 16: 119-142
- Hormone Therapy in Menopause: Concepts, Controversies, and Approach to Treatment.Endocrine Reviews. 2021; 42: 720-752
- Estrogen signaling in arcuate Kiss1 neurons suppresses a sex-dependent female circuit promoting dense strong bones.Nat Commun. 2019; 10: 163
- Transgender bone health.Maturitas. 2019; 127: 35-42
Minkler M, Wallerstein N (2011): Community-Based Participatroy Research for Health: From Process to Outcomes. John Wiley & Sons.
- Participation in Cancer Clinical Trials: Race-, Sex-, and Age-Based Disparities.Journal of the American Medical Association. 2004; 291: 2720-2726
- Health Equity Tourism: Ravaging the Justice Landscape.J Med Syst. 2022; 46: 17
- Exploring the diversity of gender and sexual orientation identities in an online sample of transgender individuals.Journal of Sex Research. 2012; 49: 244-254
- Capturing the social demographics of hidden sexual minorities: An internet study of the transgender population in the United States.Sex Res Soc Policy. 2007; 4: 50-64
- Non-binary or genderqueer genders.International Review of Psychiatry. 2016; 28: 95-102
- The Case Against Autogynephilia.International Journal of Transgenderism. 2010; 12: 176-187
- Being Transgender: The Experience of Transgender Identity Development.null. 2014; 61: 1727-1758
- Methodological Critique of Littman’s (2018) Parental-Respondents Accounts of “Rapid-Onset Gender Dysphoria.Arch Sex Behav. 2020; 49: 61-66
- Systemic inequalities for LGBTQ professionals in STEM.Sci Adv. 2021; 7eabe0933
- STEM Pride: Perspectives from transgender, nonbinary, and genderqueer scientists.Cell. 2021; 184: 3352-3355
Carey B (2007, August 21): Criticism of Gender Theory, and a Scientist Under Siege. New York Times F1, F6.
- Considerations for clinical work and research with transgender and gender diverse individuals.the Behavior Therapist. 2018; 41: 253-262
Clements-Nolle K, Bachrach A (2008): CBPR with a hidden population: the transgender community health project a decade later. Community-Based Research for Health: From Process to Outcomes. New Jersey: Jossey-Bass Publishing.
- Community-Based Participatory Research: A New and Not-So-New Approach to HIV/AIDS Prevention, Care, and Treatment.AIDS Education and Prevention. 2010; 22: 173-183
- I Don’t Think This Is Theoretical; This Is Our Lives”: How Erasure Impacts Health Care for Transgender People.Journal of the Association of Nurses in AIDS Care. 2009; 20: 348-361
- Biocultural approaches to transgender and gender diverse experience and health: Integrating biomarkers and advancing gender/sex research.Am J Hum Biol. 2021; 33https://doi.org/10.1002/ajhb.23555